A Mad2-Mediated Translational Regulatory Mechanism Promoting S-Phase Cyclin Synthesis Controls Origin Firing and Survival to Replication Stress.
Gay S, Piccini D, Bruhn C, Ricciardi S, Soffientini P, Carotenuto W, Biffo S, Foiani M.
Mol Cell. (2018) 70(4):628-638

Magnetically driven drug delivery systems improving targeted immunotherapy for colon-rectal cancer.
Grifantini R, Taranta M, Gherardini L, Naldi I, Parri M, Grandi A, Giannetti A, Tombelli S, Lucarini G, Ricotti L, Campagnoli S, De Camilli E, Pelosi G, Baldini F, Menciassi A, Viale G, Pileri P, Cinti C.
J Control Release (2018) pii: S0168-3659(18)30254-2 [Epub ahead of print]

Enhancer reprogramming in tumor progression: a new route towards cancer cell plasticity.
Fagnocchi L, Poli V, Zippo A.
Cell Mol Life Science (2018) s00018-018-2820-1 [Epub ahead of print]

Pathogenicity of in-vivo generated intestinal Th17 lymphocytes is IFNγ dependent.
Nizzoli G, Burrello C, Cribiù FM, Lovati G, Ercoli G, Botti F, Trombetta E, Porretti L, Todoerti K, Neri A, Giuffrè MR, Geginat J, Vecchi M, Rescigno M, Paroni M, Caprioli F, Facciotti F.
J Crohns Colitis (2018) ecco-jcc/jjy051 [Epub ahead of print]

Dynamic and Cell-Specific DACH1 Expression in Human Neocortical and Striatal Development.
Castiglioni V, Faedo A, Onorati M, Bocchi VD, Li Z, Iennaco R, Vuono R, Bulfamante GP, Muzio L, Martino G, Sestan N, Barker RA, Cattaneo E.
Cerebral Cortex (2018) cercor/bhy092 [Epub ahead of print]

Sumoylation and ubiquitylation crosstalk in the control of ΔNp63α protein stability.
Ranieri M, Vivo M, De Simone M, Guerrini L, Pollice A, La Mantia G, Calabrò V.
Gene (2018) 645:34-40.

Enhancing Antibody Serodiagnosis Using a Controlled Peptide Coimmobilization Strategy.
Sola L, Gagni P, D’Annessa I, Capelli R, Bertino C, Romanato A, Damin F, Bergamaschi G, Marchisio E, Cuzzocrea A, Bombaci M, Grifantini R, Chiari M, Colombo G, Gori A, Cretich M.
ACS Infect Dis (2018) 8b00014

How Polycomb-Mediated Cell Memory Deals With a Changing Environment: Variations in PcG complexes and proteins assortment convey plasticity to epigenetic regulation as a response to environment.
Marasca F, Bodega B, Orlando V.
Bioessays. (2018) 40(4):e1700137

Modulation of innate and adaptive immunity by P2X ion channels.
Di Virgilio F, Sarti AC, Grassi F.
Curr Opin Immunol. (2018) 52:51-59 [Epub ahead of print]

Successful sequential therapy with rituximab and belimumab in patients with active systemic lupus erythematosus: a case series.
Gualtierotti R, Borghi MO, Gerosa M, Schioppo T, Larghi P, Geginat J, Meroni PL
Clin Exp Rheumatol. 2018 Feb 27. [Epub ahead of print]

MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state.
Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, Miluzio A, Gaudioso G, Vaira V, Turdo A, Giaggianesi M, Chinnici A, Lipari E, Bicciato S, Bosari S, Todaro M, Zippo A.
Nat Commun. (2018) 9(1):1024.

Intestinal IFN-γ-producing Tr1-cells co-express CCR5 and PD-1, and down-regulate IL-10 in the inflamed gut of IBD patients.
Alfen JS, Larghi P, Facciotti F, Gagliani N, Bosotti R, Paroni M, Maglie S, Gruarin P, Vasco CM, Ranzani V, Frusteri C, Iseppon A, Moro M, Crosti MC, Gatti S, Pagani M, Caprioli F, Abrignani S, Flavell RA, Geginat J.
J Allergy Clin Immunol (2018) [Epub ahead of print]

Lack of Methyl-CpG Binding Protein 2 (MeCP2) Affects Cell Fate Refinement During Embryonic Cortical Development.
Cobolli Gigli C, Scaramuzza L, De Simone M, Rossi RL, Pozzi D, Pagani M, Landsberger N, Bedogni F.
Cereb Cortex. (2018) [Epub ahead of print]

Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes.
Conforti P, Besusso D, Bocchia VD,  Faedo A, Cesana E, Rossetti G, Ranzani V,  Svendsend CN, Thompson LM, Toselli M, Biella G, Pagani M, Cattaneo E.
Proc Natl Acad Sci U S A. (2017) 115(4):E762-E771.

INGM RESEARCH IS SUPPORTED BY